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Dietary Limitations: Many "fad" diets focus on extreme calorie reduction, which can slow metabolism over time and lead to nutrient deficiencies
The NICE Clinical Knowledge Summary for vitamin B12 deficiency outlines specific treatment schedules: for patients without neurological symptoms, hydroxocobalamin 1 mg intramuscularly three times a week for 2 weeks
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As the levels find their equilibrium, these signs usually dissipate within a span of a few days to a couple of weeks
This creates a net negative balance within adipocytes, resulting in decreased lipid droplet size and eventual adipocyte shrinkage
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