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For example, the SELECT trial showed a 20% improvement in major cardiovascular events (i.e., heart attacks, strokes, and deaths from those cases) in adults on weekly semaglutide who were overweight or obese (without diabetes) and with preexisting cardiovascular disease, as well as an improvement in all-cause mortality of 19%
Nat Rev Rheumatol 9(11):674686
Rather than abandoning protein, GLP-1 users appeared to be placing greater value on nutrient density and other attributes typically associated with higher-margin food products
Meta-analysis and systematic review
It's what lets the drug latch onto its receptor and do its job, whether that's quieting appetite, slowing how fast your stomach empties, or helping your body handle blood sugar
