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Phase II and III clinical trials are currently underway to evaluate its treatment potential and safety in MASH

Drugs and chemicals Methotrexate Methotrexate was purchased from Hikma Specialized Pharmaceuticals Company, Egypt, as vials, each one has 50 mg of MTX

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PTS 6-pyruvoyltetrahydropterin synthase this enzyme is not only responsible for dopamine and serotonin regulation[20], it also creates nitric oxide synthetase, or NOS, which is an important chemical in the body that promotes heart health and blood vessel formation.[21] SPR Sepiapterin reductase a gene that dictates serotonin and dopamine levels in the brain, and deficiencies can lead to muscle regulation issues such as involuntary muscle contractions.[22] However, for therapeutic purposes, the type of magnesium is crucial to its delivery to the appropriate tissue and for its efficacy in improving peoples health in the many ways outlined above

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